Advanced Ultrafiltration Technology for Uncompromised Purity
Chlory UF-Membrane Refining and Impurity Removal System leveragesprecision ultrafiltration (UF) membrane technologyto achieve molecular-level separation of macromolecules, colloids, and microorganisms. Designed for pharmaceutical, biotechnology, and high-purity chemical applications, this system operates at ≤0.7 MPa pressure and ambient temperatures (5–45°C/75°C), eliminating thermal degradation risks while ensuring >99% removal of impurities. As a national high-tech enterprise with 40+ patents and 2,000+ industrial deployments, Xihe Flow guarantees compliance with pharmacopeia standards for critical processes like injectable purification and biologics desalination.
Process Flow: Molecular Sieving for Absolute Clarity
The UF system employs apressure-driven cross-flow filtration processthat separates impurities without chemical additives:
- Feed Pressurization: Raw material enters under controlled pressure (≤0.7 MPa).
- Selective Separation: UF membranes retain macromolecules (>1,000–500,000 Da), colloids, and microorganisms while allowing solvents and small molecules to permeate.
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Output Streams:
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Retentate: Concentrated impurities (e.g., endotoxins, proteins) for disposal.
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Permeate: Purified fluid ready for final formulation.
Closed-loop, automated, and ISO-compliant operation.
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The membrane separation process relies on precise molecular-level screening. Feed liquid containing water, small molecules, and large particles passes through semi-permeable membranes. Water and small molecules permeate, while large particles are retained as concentrate.
Key Advantages
- Pharmaceutical-Grade Purity: Removes >99% endotoxins, viruses, and colloids for injectables (e.g., WFI, monoclonal antibodies).
- Material Integrity: Gentle room-temperature processing preserves APIs, enzymes, and heat-sensitive compounds.
- Energy Efficiency: 70% lower energy consumption vs. centrifugation/diatomaceous earth filtration.
- Zero Contamination Risk: No chemical additives; fully autoclavable (SIP/CIP compatible).
- Scalability: Modular design supports capacities from 50 to 8,000 kg/h.
- Cost Savings: Membranes reusable for 2–3 years with cleanable surfaces.
Technical Specifications
| Model | Capacity (kg/h) | Power (kW) | Pressure (MPa) | Temperature (°C) |
|---|---|---|---|---|
| XH-UF4040-1X | 50–100 | 2.2 | ≤0.7 | 5–45/75 |
| XH-UF4040-2X | 100–150 | 2.2 | ≤0.7 | 5–45/75 |
| XH-UF4040-4X | 150–250 | 4.0 | ≤0.7 | 5–45/75 |
| XH-UF4040-6X | 250–300 | 5.5 | ≤0.7 | 5–45/75 |
| XH-UF8040-1X | 150–300 | 4.0 | ≤0.7 | 5–45/75 |
| XH-UF8040-2X | 300–600 | 4.0 | ≤0.7 | 5–45/75 |
| XH-UF8040-4X | 600–1,000 | 7.5 | ≤0.7 | 5–45/75 |
| XH-UF8040-6X | 1,000–1,500 | 7.5 | ≤0.7 | 5–45/75 |
| XH-UF8040-8X | 1,500–2,000 | 7.5 | ≤0.7 | 5–45/75 |
| XH-UF8040-9X | 1,800–2,500 | 11 | ≤0.7 | 5–45/75 |
| XH-UF8040-12X | 2,500–3,500 | 11 | ≤0.7 | 5–45/75 |
| XH-UF8040-15X | 3,500–4,500 | 15 | ≤0.7 | 5–45/75 |
| XH-UF8040-16X | 4,000–5,000 | 22 | ≤0.7 | 5–45/75 |
| XH-UF8040-18X | 4,500–5,500 | 22 | ≤0.7 | 5–45/75 |
| XH-UF8040-20X | 5,000–6,000 | 22 | ≤0.7 | 5–45/75 |
| XH-UF8040-24X | 6,000–8,000 | 30 | ≤0.7 | 5–45/75 |
Custom configurations available for specialized needs.
Industry Applications
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Pharmaceuticals:
- Purification of injections (e.g., double Coptis injection), oral liquids, and biologics.
- Removal of pyrogens and aggregates in monoclonal antibodies.
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Biotech:
- Fermentation broth clarification and enzyme purification.
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Food & Beverage:
- Juice/wine clarification and stability enhancement.
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Chemicals:
- Polymer fractionation and catalyst recovery.
Product Category
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