Glucosamine Hydrochloride Membrane Purification & Concentration Technology
Background Introduction
As a health-care pharmaceutical product, glucosamine hydrochloride provides excellent protective effects on human joints. The mature production process of glucosamine hydrochloride is the fermentation method. The fermentation broth produced by this process features complex components, containing a large amount of culture medium, mycelium, miscellaneous proteins, pigments and other impurities. Combined processes are required to separate and purify high-purity glucosamine hydrochloride products.
Application of Membrane Separation Technology in Glucosamine Hydrochloride Production
Based on years of practical experience in membrane separation technology application, BluewavBio applies advanced membrane separation technology to the production process of glucosamine hydrochloride according to the material properties of glucosamine hydrochloride, effectively improving product quality, reducing energy consumption and saving production costs.
Membrane Purification and Concentration Process of Glucosamine Hydrochloride
Process Introduction
(1) The concentrated solution after ceramic membrane separation is treated by plate-and-frame pressure filtration. The filter cake consisting of thallus and culture medium residues can be used as feed materials.
(2) The low-pressure membrane concentration system increases the concentration of glucosamine hydrochloride to 50g/L.
(3) The medium-pressure membrane concentration system increases the concentration of glucosamine hydrochloride to more than 100g/L.
(4) The permeate generated from the two-stage concentration process can be recycled to the previous extraction process, with the glucosamine content in the permeate lower than 0.2g/L.
(5) The MVR system consumes far less energy than traditional thermal concentration. It adopts a steam compressor to compress steam, improve steam utilization rate and greatly save steam consumption.
Technical Characteristics of Membrane Separation System Equipment
(1) Adopts advanced nano-scale membrane elements with selective separation performance, realizing separation and concentration at the molecular level.
(2) The unique cross-flow operation process solves the problem of easy blockage of filter and separation elements.
(3) Reduces solvent consumption, achieves energy conservation and emission reduction, and complies with national environmental protection policies.
(4) Concentration is carried out at normal or low temperature without damaging heat-sensitive components. The concentration process can remove inorganic salt components, reduce the ash content of final products and improve product quality.
(5) It is a pure physical separation process with no chemical agents or auxiliaries added.
(6) Simplifies the production process, shortens the production cycle, and improves production efficiency and product yield.
(7) Modular membrane design can be directly embedded into the existing production process with convenient membrane component replacement.
(8) Equipped with automatic program control and online cleaning and maintenance functions, reducing workload and improving production efficiency.
(9) The permeate from membrane concentration can be recycled to the extraction section, reducing water consumption and wastewater discharge, alleviating the enterprise's environmental protection pressure and conforming to national environmental protection policies.
Typical Applications
Glucosamine hydrochloride and similar fermented products.